The fundamental principle of the THz time-domain spectroscopy technology is to utilize the THz electric field produced by femtosecond pulse which could detect time-solving. By using Fourier transformation we could get the spectral information of the article. Most of the vibration and rotational level of the macromolecule are in the band of THz, thus we could analyze and identify the structure of the matter and physical property by its characteristic frequency. Currently, it is certain that this technology could be used in the field of pharmaceutics, cultural heritage and national defense. In the field of pharmaceutics, THz spectrum analyzer could be used to detect the crystal and non-crystal in the medicine during the process of production. Besides, the spectrum analyzer could quantify the pharmaceutical compositions and the study of solid medicine phase transition with the support of chemometrics. In the field of cultural heritage, the analyzer could be used to analyze the chemical composition of the mixture which is used in the material of the heritage. The analyzer could be used to detect the explosive and poisonous gas in the field of national defense. In the field of biomedicine, it could also be used in the research of oncology, such as skin cancer and breast cancer, as the spectrum absorption of the THz radiation is different for normal tissue and cancer tissue.

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